Year : 2011  |  Volume : 2  |  Issue : 2  |  Page : 71-78

Alstonia scholaris: It's Phytochemistry and pharmacology

1 Department of Pharmacology, Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana, India
2 Rayat college of Pharmacy, Ropar, Punjab, India

Correspondence Address:
Dhirender Kaushik
Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/2229-5186.82970

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Complementary therapies based on herbal medicines are the world's oldest form of medicine and recent reports suggest that such therapies still enjoy vast popularity, especially in developing countries where most of the population does not have easy access to modern medicine. Alstonia scholaris (L.) R.Br (Apocynaceae) is an evergreen tropical tree native to Indian sub-continent and South East Asia, having grayish rough bark and milky sap rich in poisonous alkaloid. It is reported to contain various iridoids, alkaloids, coumarins, flavonoids, leucoanthocyanins, reducing sugars, simple phenolics, steroids, saponins and tannins. It has been reported to possess antimicrobial, antiamoebic, antidiarrheal, antiplasmodial, hepatoprotective, immunomodulatory, anticancer, antiasthmatic, free radical scavenging, antioxidant, analgesic, anti-inflammatory, antiulcer, antifertility and wound healing activities. In other parts of the world, it is used as a source cure against bacterial infection, malarial fever, toothache, rheumatism, snakebite, dysentery, bowl disorder, etc. Reports on the pharmacological activities of many isolated constituents from A. scholaris (L.) R.Br are lacking, which warrants further pharmacological studies.

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