ORIGINAL ARTICLE
Year : 2012  |  Volume : 3  |  Issue : 1  |  Page : 29-36

A study of psychiatric morbidity in patients of peptic ulcer diseases


Department of Psychiatry, Government Medical College and Rajindra Hospital, Patiala, Punjab, India

Correspondence Address:
Jagpal Singh Klair
Government Medical College, Patiala-147 001, Punjab
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2229-5186.94310

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Aims and Objectives: To study the prevalence of psychiatric morbidity among patients of peptic ulcer disease and to study the patients of peptic ulcer disease with psychiatric morbidity in comparison to patients of peptic ulcer disease without psychiatric morbidity on following variables: sociodemographic variables and attributes/risk factors of peptic ulcer disease. Materials and Methods: Fifty cases of clinically proven acid peptic diseases and 30 cases of the control group were screened in department of General Medicine, outdoor as well as indoor patients. Instruments applied for the purpose of the study were Personal Bio-data Performa (Appendix-I), (SCL)- 80 (Appendix-II), Hamilton rating scale for anxiety and depression, (P.S.L.E.); clinical diagnosis of psychiatric disorders was made as per ICD- 10 criteria. Data collected shall be subjected to statistical analysis. Results and Findings: The psychiatric morbidity was significantly (P<0.01) higher in study group patients with SCL-80 mean score of 66.36 compared to 37.53 in control group subjects. It was observed that on the basis of SCL-80 scores, significantly (P<0.001) higher psychiatric morbidity was present in 29 patients from the study group (58% of cases) while four subjects showed psychiatric morbidity in the control group (13.33% of cases). The symptoms of depression were seen significantly (P<0.01) higher in study group patients with a mean score of 11.52 compared to control group subjects with a mean score of 3.8. The anxiety symptoms were found significantly (P<0.01) higher in study group patients with a mean score of 6.22 compared to 2.76 in control group subjects. As per ICD-10 criteria, a significantly higher number of patients in the study group were diagnosed as depression (P<0.05), generalized anxiety disorder (P<0.02) and somatization (P<0.05) as the percentage was 24%, 26%, and 18% compared to 6.67%, 6.67%, and 3.33% in control group subjects. Further, 32% of patients in the study group were shown to have a significantly (P<0.05) stronger family history of acid peptic disease compared to 13.33% of subjects in the control group. A significantly higher number of patients with psychiatric morbidity, i.e. 34.48%, were diagnosed as a case of acid peptic disease in the late age of 41-50 years compared to 19.04% of patients without psychiatric morbidity. A significantly higher (P<0.001) number of patients (51.72%) with psychiatric morbidity had longer duration of acid peptic disease illness, i.e. >10 years, compared to 23.80% in patients without psychiatric morbidity. Lastly, 48.27% of patients with psychiatric morbidity had significantly (P<0.01) stronger family history of acid peptic disease compared to 9.52% in patients without psychiatric morbidity. Conclusions: There is a significant relationship between the peptic ulcer disease and the various psychiatric morbidity factors as illustrated from the findings of this study.


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