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Table of Contents
April-June 2010
Volume 1 | Issue 2
Page Nos. 1-34
Online since Thursday, October 07, 2010
Accessed 19,311 times.
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LETTER TO EDITOR
Is the failure of expression of recombinant protein due to qiRNA?
p. 1
J Francis Borgio
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REVIEW ARTICLES
Nanoemulsion: A new concept of delivery system
p. 2
Nitin Sharma, Mayank Bansal, Sharad Visht, PK Sharma, GT Kulkarni
Nanoemulsion has been identified as a promising delivery system for various drugs including biopharmaceuticals. Nanoemulsion is a heterogeneous system composed of one immiscible liquid dispersed as droplets within another liquid. The droplets size of nano emulsion is between 20 to 500 nm. Diameter and surface properties of droplets of nanoemulsion plays an important role in the biological behavior of the formulation. Small droplet sizes lead to transparent emulsions so that product appearance is not altered by the addition of an oil phase. In this paper various aspects of nanoemulsion have been discussed including advantages, disadvantages and methods of preparation. Furthermore new approaches of stability of formulation, effect of types and concentration of surfactant, process variables and method are also discussed to improve the stability of nanoemulsion formulation
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Career opportunities in pharmacy profession: An informative note
p. 7
Sandhya Bawa, Rajiv K Tonk, Jyoti A Tonk, Suresh Kumar, Sumit Singla
Pharmacy profession is always a choice of preference for the medical aspirants. There are many other medical or paramedical courses but from career opportunities point of view, the profession of pharmacy provides many job opportunities in this field. Now a day's pharma industry and profession are experiencing rapid changes due to advanced technological innovations and ideas sweeping across the world. Hence these changes give better opportunities to the pharmacy profession and it is imperative to evolve a Pharmacy academic programme that suits the basic thirst of the nation like providing medicines at affordable prices, community health care etc.
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Supercritical fluid chromatography-A Hybrid of GC and LC
p. 12
Neha Sethi, Ankit Anand, Garima Jain, Kona S Srinivas, Kaushal K Chandrul
High performance specifications and unique functionality of chromatographic techniques is a demand of pharmaceutical industry and research. This leads to the origin of Supercritical Fluid Chromatography (SFC). It is a rapidly expanding analytical technique. The main feature that differentiates SFC from other chromatographic techniques is the replacement of either the liquid or gas mobile phase with a supercritical fluid mobile phase. It is considered a hybrid of GC and LC technique. High diffusion coefficient and low viscosity of supercritical fluids is responsible for high speed analysis, high efficiency and high sensitivity. Low mobile-phase flow rate, density programming and compatability with GC and LC detectors make SFC a versatile chromatographic technique in analytical research and development. It has a unique characteristic of analyzing thermo labile or non-volatile substances. This review highlights the role of supercritical fluid chromatography in the separation of polymers, thermally labile pesticides, fatty acids, metal chelates and organometallic compounds, chiral and achiral molecules, identification and analysis of polar samples, explosives, drugs of abuse and application of SFC in forensic science (fingerprinting).
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Multitude potential of wheatgrass juice (Green Blood): An overview
p. 23
Swati Padalia, Sushma Drabu, Indira Raheja, Alka Gupta, Mamta Dhamija
Wheatgrass is the young grass of the common wheat plant Triticum aestivum Linn., family Poeaceae (Graminae). It is commonly known as the "green blood" due to its high chlorophyll content which accounts for 70% of its chemical constituents. It contains a plethora of vitamins, minerals, amino acids and vital enzymes like superoxide dismutase and cytochrome oxidase. The vitamin content makes it an important adjuvant in anti-allergic and anti-asthmatic treatment, while the enzymes play a pivotal role in the anticancer approach of this herbal drug. A notable feature of the wheatgrass juice is its bioflavonoid content which are the naturally occurring antioxidants and account for many of its clinical utilities such as management of inflammatory bowel disease and as a general detoxi-fier. However, the most remarkable feature of the wheatgrass juice is its high chlorophyll content. Chlorophyll bears structural similarity to hemoglobin and has been found to regenerate or act as a substitute of hemoglobin in hemoglobin deficiency conditions. This might be the reason behind the utility of wheatgrass in clinical conditions like thalassemia and hemolytic anemia. The present article focuses onto the various studies emphasizing the multitude potentials of wheatgrass.
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Intellectual Properties Rights-A strong determinant of economic growth in agriculture
p. 29
Love Kumar Singh, Munmun Rai, Manju Chaudhary
In the past few decades the subject of intellectual property rights (IPRs) has occupied center stage in debates about globalization, economic development and poverty elimination. This study concerns the strengthening of IPRs in the plant breeding industry and its effect on agriculture in India. In India, most of the population relies on agriculture for its livelihood. India is self-sufficient in wheat and paddy, but deficient in other agricultural products. Patents are good indicators of research and development output. Patent analysis makes it possible to map out the trend of technological change and life cycle of a technology - growth, development, maturity and decline. Patent information and patent statistical analysis have been used for examining present, technological status and to forecast future trends. One can determine the directions of corporate R&D and market interests by analyzing patent data. The present study is an attempt to analyze patents granted in India in the field of agriculture and importance of biotechnology-based innovations in agriculture
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© Chronicles of Young Scientists | Published by
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Online since 05
th
October, 2010